Resume
Basic Information: Yang Bin, born in July 1984, native of Zhangshu, Jiangxi. Researcher at the National Key Laboratory of Pig Genetic Improvement and Germplasm Innovation, Jiangxi Agricultural University.
Education and Work Experience:
· January 2012 – Present: Assistant Researcher, Associate Researcher, and Researcher at Jiangxi Agricultural University
· May 2012 – September 2014: Postdoctoral Fellow at Jiangxi Agricultural University
· October 2012 – January 2013: Visiting Scholar at Icahn School of Medicine at Mount Sinai, New York, USA
· November 2008 – August 2011: Ph.D. at the Autonomous University of Barcelona’s Faculty of Veterinary Medicine and Center for Research in Agricultural Genomics (CRAG), Spain
· September 2005 – July 2008: Master's Degree at Jiangxi Agricultural University
Major Work and Achievements: Focused on pig genetic improvement, combining high-throughput molecular sequencing technologies to conduct research on the genetic mechanisms underlying complex economic traits in pigs.
Representative publications：
1. Ziqi Ling*, Jing Li, Tao Jiang, Zhen Zhang, Yaling Zhu, Zhimin Zhou, Jiawen Yang, Xinkai Tong,Bin Yang* & Lusheng Huang*. Omics-based construction of regulatory variants can be applied to help decipher pig liver-related traits. Communications Biology. 2024. 7:381. DOI:10.1038/s42003-024-06050-7
2. Tao Jiang#, Zhimin Zhou#, Ziqi Ling, Qing Zhang, Zhongzi Wu, Jiawen Yang, Siyu Yang,Bin Yang* and Lusheng Huang*. Pig H3K4me3, H3K27ac and gene expression profiles reveal productive tissue-specific activity of transposable elements. Zoological Research. 2023 DOI:10.24272/j.issn.2095-8137.2023.060.
3. Yanyuan Xiao, Qing Zhang, Fei Huang, Lin Rao, Tianxiong Yao, Siyu Yang, Lei Xie, Xiaoxiao Zou, Liping Cai, Jiawen Yang,Bin Yang* and Lusheng Huang*. Single cell profiling pig caecum at various developmental stages. Zoological Research. 2023 DOI:10.24272/j.issn.2095-8137.2023.007.
4. Leilei Cui#,Bin Yang#, Shijun Xiao, Jun Gao, Amelie Baud, Delyth Graham, Martin McBride, Anna Dominiczak, Sebastian Schafer, Regina Lopez Aumatell, Carme Mont, Albert Fernandez Teruel, Norbert Hubner, Jonathan Flint, Richard Mott* and Lusheng Huang*. Dominance is common in mammals and is associated with trans-acting gene expression and alternative splicing. Genome Biology. 2023 Sep 29; 24(1):215.doi:10.1186/s13059-023-03060-2.
5. Jiawen Yang#, Leilei Cui#, Yifeng Zhang, Ziqi Ling, Zhou Zhang, Yizhong Huang, Junwu Ma, Shijun Xiao,Bin Yang* and Lusheng Huang*. Unravelling the genetic basis for skeletal muscle mitochondrial DNA copy number variations in pigs. Science China Life Sciences.doi.org/10.1007/s11427-022-2397-1.
6. Siyu Yang, Dong Chen, Lei Xie, Xiaoxiao Zou, Yanyuan Xiao, Lin Rao, Tianxiong Yao, Qing Zhang, Liping Cai, Fei Huang,Bin Yang*, Lusheng Huang*. Developmental dynamics of the single nucleus regulatory landscape of pig hippocampus. Science China Life Sciences. 2023 Jul 6. doi:10.1007/s11427-022-2345-2.
7. Tao Jiang#, Ziqi Ling#, Zhimin Zhou, Xiaoyun Chen, Liqing Chen, Sha Liu, Yingchun Sun, Jiawen Yang,Bin Yang*, Jianzhen Huang*, and Lusheng Huang. Construction of a transposase accessible chromatin landscape reveals chromatin state of repeat elements and potential causal variant for complex traits in pigs. Journal of Animal Science and Biotechnology. 2022 Oct 11; 13(1):112. doi:1186/s40104-022-00767-3.
8. Zhimin Zhou#, Tao Jiang#, Yaling Zhu, Ziqi Ling,Bin Yang* and Lusheng Huang*. A comparative investigation on H3K27ac enhancer activities in the brain and liver tissues between wild boars and domesticated pigs. Evolutionary Applications. 2022 Aug 16; 15(8):1281-1290. doi:10.1111/eva.13461. eCollection 2022 Aug.
9. Huanfa Gong#, Weiwei Liu#, Zhongzi Wu, Mingpeng Zhang, Yingchun Sun, Ziqi Ling, Shijun Xiao, Huashui Ai, Yuyun XIng,Bin Yang* and Lusheng Huang*. Evolutionary insights into porcine genomic structural variations based on a novel-constructed dataset from 24 worldwide diverse populations. Evolutionary Applications. 2022 July,doi.org/10.1111/eva.13455.
10. Yingchun Sun, Yanyuan Xiao, Chenyu Li, Jiawen Yang, Siyu Yang,Bin Yang* and Lusheng Huang*. A parallel survey on the fatty acid composition in backfat and longissimus lumborum and comparison of their associations with growth and carcass traits in pigs. Livestock Science. 2022 September, 104984. doi: 10.1016/j.livsci.2022.104984
11. Yaling Zhu, Zhimin Zhou, Tao Huang, Zhen Zhang, Wanbo Li, Ziqi Ling, Tao Jiang, Jiawen Yang, Siyu Yang, Yanyuan Xiao, Carole Charlier, Michel Georges,Bin Yang* & Lusheng Huang*. Mapping and analysis of a spatiotemporal H3K27ac and gene expression spectrum in pigs. Science China Life Sciences.2022 Jan 27. doi: 10.1007/s11427-021-2034-5.
12. Zhongzi Wu; Huanfa Gong; Zhimin Zhou; Tao Jiang; Ziqi Lin; Jing Li; Shijun Xiao;Bin Yang*; Lusheng Huang*. Mapping short tandem repeats for liver gene expression traits helps prioritize potential causal variants for complex traits in pigs. Journal of Animal Science and Biotechnology.2022 Jan 17;13(1):8.
13. Xianxian Liu#, Junjie Zhang#, Xinwei Xiong, Congying Chen, Yuyun Xing, Yanyu Duan, Shijun Xiao,Bin Yang*, Junwu Ma*.An integrative analysis of transcriptome and GWAS data to identify potential candidate genes influencing meat quality traits in pigs. Frontiers in Genetics.2021 Oct 21;12:748070.
14. Qing Zhang#, Jing Li#, Yifeng Zhang, Huanfa Gong, Zhimin Zhou, Wenwu Xu, Zhongzi Wu, Yingchun Sun, Tao Jiang, Ziqi Ling, Shijun Xiao, Lusheng Huang* andBin Yang*.Whole-genome sequence-based association study for immune cells in an eight-breed pig heterogeneous population. Journal of Genetics and Genomics. 2021Sep 30;S1673-8527(21)00317-9. doi: 10.1016/j.jgg.2021.09.003.
15. Zhimin Zhou#, Yaling Zhu#, Zhen Zhang, Tao Jiang, Ziqi Ling,Bin Yang* and Wanbo Li*. Comparative Analysis of Promoters and Enhancers in the Pituitary Glands of the Bama Xiang and Large White pigs. Frontiers in Genetics. 2021Jul 23;12:697994 doi:10.3389/fgene.2021.697994.
16. Zhongzi Wu, Huanfa Gong, Mingpeng Zhang, Xinkai Tong, Huashui Ai, Shijun Xiao, Miguel Perez-Enciso,Bin Yang* and Lusheng Huang*. A worldwide map of swine short tandem repeats andtheir associations with evolution and environmental adaptation. Genetics Selection Evolution. 2021. Apr 23;53(1):39. doi.org/10.1186/s12711-021-00631-4.
17. Yifeng Zhang, Yingchun Sun, Zhongzi Wu, Xinwei Xiong, Junjie Zhang, Junwu Ma, Shijun Xiao, Lusheng Huang* andBin Yang*.Subcutaneous and intramuscular fat transcriptomes differ largely in network organization and association with fat deposition traits in pigs. Science China Life Sciences.2021 Jan 27. doi: 10.1007/s11427-020-1824-7.
18. Qing Zhang#, Jing Li#, Tao Huang, Yifeng Zhang, Wenwu Xu, Lusheng Huang, Huashui Ai and Bin Yang*. Impacts of Mycoplasma loads and lung lesions on immune and hematological statuses of pigs in an eight-breed cross heterogeneous population. Journal of Animal Science. 2020 Aug 1;98(8):skaa235.Doi:10.1093/jas/skaa235.
19. Yizhong Huang#, Lisheng Zhou#, Junjie Zhang 1, Xianxian Liu 1, Yifeng Zhang 1, Liping Cai 1, Wanchang Zhang 1, Leilei Cui 1, Jie Yang 1, Jiuxiu Ji 1, Shijun Xiao 1, Huashui Ai 1, Congying Chen 1, Junwu Ma*, Bin Yang*, Lusheng Huang*.A Large-Scale Comparison of Meat Quality and Intramuscular Fatty Acid Composition Among Three Chinese Indigenous Pig Breeds. Meat Science. 2020 May 11;168:108182. doi:10.1016/j.meatsci.2020.108182
