Name:Li Xin
Gender:Male
Date of birth:1997.04
E-mail:lixin_andy@163.com
Education Background：
2015.09-2019.06 College of Animal Science, South China Agricultural University, Bachelor of Animal Science.
2019.09-2024.06 College of Animal Sciences, Zhejiang University, Animal Nutrition and Feed Science, Philosophy Doctor, supervisor: Professor Caihong Hu.
Participate in scientific research projects:：
National Natural Science Foundation of China: The role of AMPK-PINK1/Parkin-mediated mitophagy in the repair of intestinal barrier damage induced by oxidative stress in piglets and its nutritional regulation.
National Natural Science Foundation of China: Role of mitochondria-associatedendoplasmic reticulummembranes in the repair of intestinal barrierinjury in piglets under oxidative stress and nutritional regulation.
National Natural Science Foundation of China: Mechanism and nutritional regulation of endoplasmic reticulum-mitochondrial calcium signal-mediated intestinal epithelial barrier injury in piglets induced by DON
Natural Science Foundation of Zhejiang Province: Mechanism of sodium butyrate promoting intestinal injury repair in piglets under oxidative stress through AMPK-mediated mitophagy
Awards
Zhejiang University National Scholarship 2023
Zhejiang University AoteqiScholarship 2022
Papers:
1. Li Xin, Gou Feiyang, Xiao Kan, Zhu Jiang, Lin Qian, Yu Minjie, Hong Qihua, Hu Caihong. (2023). Effects of DON on mitochondrial function, endoplasmic reticulum stress, and endoplasmic reticulum mitochondria contact sites in the jejunum of piglets. Journal of Agricultural and Food Chemistry, 71, 36, 13234–13243.
2. Li Xin, Zhu Jiang, Lin Qian, Yu Minjie, Lu Jianjun, Feng Jie, Hu Caihong. (2022). Effects of curcumin on mitochondrial function, endoplasmic reticulum stress and mitochondria-associated endoplasmic reticulum membranes in oxidative stress piglets. Journal of Agricultural and Food Chemistry, 2022, 70, 29, 8974–8985.
3. Li Xin, Wang Chunchun, Zhu Jiang, Lin Qian, Yu Minjie, Wen Jiashu, Feng Jie, Hu Caihong. (2022). Sodium butyrate ameliorates oxidative stress-induced intestinal epithelium barrier injury and mitochondrial damage through AMPK-mitophagy pathway. Oxidative Medicine and Cellular Longevity, Volume 2022, Article ID 3745135.
4. Li Xin, Wen Jiashu, Jiao Lefei, Wang Chunchun, Hong Qihua, Feng Jie, Hu Caihong. (2021). Dietary copper/zinc-loaded montmorillonite improved growth performance and intestinal barrier and changed gut microbiota in weaned piglets. Journal of Animal Physiology and Animal Nutrition, 105: 678-686.
5. Li Xin, Zhu Jiang, Gou Feiyang, Lin Qian, Yu Minjie, Hong Qihua, Hu Caihong. Deoxynivalenol induced intestinal barrier injury, mitochondrial dysfunction and calcium overload by IP3Rs-MCU calcium axis. Science of the Total Environment, 2024, 913: 169729.
6. Li Xin, Lin Qian, Gou Feiyang, Zhu Jiang, Yu Minjie, Hong Qihua, Hu Caihong. Effects of hesperidin on mitochondrial function, mitochondria-associated endoplasmic membranes and IP3Rs-MCU calcium axis in the jejunum of piglets exposed to deoxynivalenol.(2024)Food & Function, , DOI: 10.1039/d4fo00783b.
7. Hong Qihua, Li Xin, Lin Qian, Shen Zhuojun, Feng Jie, Hu Caihong. Resveratrol Improves Intestinal Morphology and Anti-Oxidation Ability in Deoxynivalenol-Challenged Piglets. (2022). Animals, 12, 311. (中科院2区/JCR Q1)
8. Lin Fanghui,Li Xin, Wen Jiashu, Wang Chunchun, Peng Yan, Feng Jie, Hu Caihong. Effects of coated sodium butyrate on performance, diarrhea, intestinal microflora and barrier function of pigs during the first 2-week post-weaning. (2020). Animal Feed Science and Technology, 263, 114464.
9. Cao Shuting, Xiao Hao,Li Xin, Zhu Jiang, Gao Jingchun, Wang Li, Hu Caihong. AMPK-PINK1/Parkin mediated mitophagy is necessary for alleviating oxidative stress-induced intestinal epithelial barrier damage and mitochondrial energy metabolism dysfunction in IPEC-J2. (2021). Antioxidants, 10(12).
10. Lin Qian, Tu Xiaodian,Li Xin, Gou Feiyang, Ding Lin, Lu Zeqing, Feng Jie, Ying Yongfei, Hu Caihong.
Effects of electrolyte balance on intestinal barrier, amino acid metabolism, and mTORC1 signaling pathway in piglets fed low-protein diets. (2024).Animal Nutrition, 17, 408-417.
11. Cao Shuting,Wang Chunchun, Yan Jintao,Li Xin, Wen Jiashu, Hu Caihong. Curcumin ameliorates oxidative stress-induced intestinal barrier injury and mitochondrial damage by promoting Parkin dependent mitophagy through AMPK-TFEB signal pathway. (2019). Free Radical Biology and Medicine, 147, 8-22.
