Gao Xiaona, is a female doctor, master tutor, and associate professor at Jiangxi Agricultural University. She graduated from Nanjing Agricultural University in 2021, during her doctoral study, she visited the University of Wisconsin-Madison in the United States. Currently, she is a member of the branch of veterinary internal medicine and Clinical Medicine of the Chinese Society of Animal Husbandry and Veterinary Medicine, as we as a member of the Branch of Animal Toxicology of the Chinese Society of Animal Husbandry and veterinary Medicine. She is a special Commissioner of Science and Technology of Jiangxi Province, as well as a key member of quality safety and environmental control of poultry industry technical system at Jiangxi Province, also she is a guidance expert of Suichuan Meat Pigeon Science and Technology Academy and Dayu Duck Science and Technology Academy of Jiangxi Province. She is an expert reviewer of many SCI journals such as Poultry science and Journal of nutritional biochemistry. And she engaged in the research of pathogenesis and prevention methods of nutritional metabolic diseases in livestock and poultry. She has presided over 1 National Natural Science Foundation project, 1 National key research and development Plan project, 1 Jiangxi Provincial Natural Science Foundation project, 1 Jiangxi Provincial Education reform project, 2 science and technology projects of Jiangxi Provincial Education Department, and 1 horizontal project, and participated in a number of National Natural Science Foundation, Provincial Natural Science Foundation and horizontal projects. She guided one national innovation and entrepreneurship project ,and three innovation of entrepreneurship projects in Jiangxi Province. In 2022, she was awarded the advanced worker of Jiangxi Agricultural University. She published more than 30 academic papers, of which more than 20 are included in SCI.
E-mail: xiaona.gao@jxau.edu.cn。
Education Experience：
[1] 2017-09 to 2021-06，Nanjing Agricultural University，Clinical veterinary medicine，Docter
[2] 2014-09 to2017-06，Jiangxi Agricultural University，Clinical veterinary medicine，Maser
[3] 2010-09 to2014-06，Qingdao Agricultural University，animalmedicine，Bachelor
WorkExperience
2021.10-Now，Jiangxi Agricultural University，lecturer
Representative research results and academic awards：
1. Chen W.#, Huang C.#, Shi Y., Li N., Wang E., Hu R., Li G., Yang F., Zhuang Y., Liu P., Hu G.,Gao X.*, Guo X.*, Investigation of the Crosstalk between GRP78/PERK/ATF-4 Signaling Pathway and Renal Apoptosis Induced by Nephropathogenic Infectious Bronchitis Virus Infection. J Virol, 2022. 96(2): p. e0142921 DOI: 10.1128/JVI.01429-21.
2. Zhou C.#,Gao X.#, Cao X., Tian G., Huang C., Guo L., Zhao Y., Hu G., Liu P., Guo X., Gut Microbiota and Serum Metabolite Potential Interactions in Growing Layer Hens Exposed to High-Ambient Temperature. Front Nutr, 2022. 9: p. 877975 DOI: 10.3389/fnut.2022.877975.
3. Li N., Huang C., Chen W., Li Z., Hu G., Li G., Liu P., Hu R., Zhuang Y., Luo J.,Gao X.*, Guo X., Nephropathogenic Infectious Bronchitis Virus Mediates Kidney Injury in Chickens via the TLR7/NF-kappaB Signaling Axis. Front Cell Infect Microbiol, 2022. 12: p. 865283 DOI: 10.3389/fcimb.2022.865283.
4. Tian G.#, Shi Y.#, Cao X., Chen W., Gu Y., Li N., Huang C., Zhuang Y., Li G., Liu P., Hu G.,Gao X.*, Guo X., Preparation of the RIPK3 Polyclonal Antibody and Its Application in Immunoassays of Nephropathogenic Infectious Bronchitis Virus-Infected Chickens. Viruses, 2022. 14(8) DOI: 10.3390/v14081747.
5. Huang C.#, Gao X. #, Shi Y., Guo L., Zhou C., Li N., Chen W., Yang F., Li G., Zhuang Y., Liu P., Hu G.*, Guo X.*, Inhibition of Hepatic AMPK Pathway Contributes to Free Fatty Acids-Induced Fatty Liver Disease in Laying Hen. Metabolites, 2022. 12(9) DOI: 10.3390/metabo12090825.
6. Du J.#, Shi Y.#, Zhou C., Guo L., Hu R., Huang C., Hu G.,Gao X.*, Guo X., Antioxidative and anti-inflammatory effects of vitamin C on the liver of laying hens under chronic heat stress. Front Vet Sci, 2022. 9: p. 1052553 DOI: 10.3389/fvets.2022.1052553.
7. Li Z.#, Zhao Y.#, Zhuang Y., Xu Z., Wu C., Liu P., Hu G., Li G., Chen W.,Gao X.*, Guo X., Effects of N-Acetyl-L-Cysteine on Serum Indices and Hypothalamic AMPK-Related Gene Expression Under Chronic Heat Stress. Front Vet Sci, 2022. 9: p. 936250 DOI: 10.3389/fvets.2022.936250.
8. Gao X.#, Liu S.#, Tan L., Ding C., Fan W., Gao Z., Li M., Tang Z., Wu Y., Xu L., Yan L., Luo Y., Song S.*, Estrogen Receptor alpha Regulates Metabolic-Associated Fatty Liver Disease by Targeting NLRP3-GSDMD Axis-Mediated Hepatocyte Pyroptosis. J Agric Food Chem, 2021. 69(48): p. 14544-14556 DOI: 10.1021/acs.jafc.1c05400.（
9. Gao X.#, Liu S., Ding C., Miao Y., Gao Z., Li M., Fan W., Tang Z., Mhlambi N. H., Yan L., Song S. *, Comparative effects of genistein and bisphenol A on non-alcoholic fatty liver disease in laying hens. Environ Pollut, 2021. 288: p. 117795 DOI: 10.1016/j.envpol.2021.117795.
10. Gao X.#, Fan W., Tan L., Shi Y., Ding C., Liu S., Miao Y., Luo Y., Shi X., Desaeger S., Song S.*, Soy isoflavones ameliorate experimental colitis by targeting ERalpha/NLRP3 inflammasome pathways. J Nutr Biochem, 2020. 83: p. 108438 DOI: 10.1016/j.jnutbio.2020.108438.
11. Gao X.#, Liu P. #, Wu C., Wang T., Liu G., Cao H., Zhang C., Hu G.*, Guo X.*, Effects of fatty liver hemorrhagic syndrome on the AMP-activated protein kinase signaling pathway in laying hens. Poult Sci, 2019. 98(5): p. 2201-2210 DOI: 10.3382/ps/pey586.
12. Huang Q.#,Gao X.#, Liu P.#, Lin H., Liu W., Liu G., Zhang J., Deng G., Zhang C., Cao H., Guo X.*, Hu G.*, The relationship between liver-kidney impairment and viral load after nephropathogenic infectious bronchitis virus infection in embryonic chickens. Poult Sci, 2017. 96(6): p. 1589-1597 DOI: 10.3382/ps/pew455.
13. Tian G#, Huang C, Li Z, Lu Z, Feng C, Zhuang Y, Li G, Liu P, Hu G,Gao X*, Guo X*. Baicalin mitigates nephropathogenic infectious bronchitis virus infection-induced spleen injury via modulation of mitophagy and macrophage polarization in Hy-Line chick. Vet Microbiol. 2023 Nov;286:109891. doi: 10.1016/j.vetmic.2023.109891. Epub 2023 Oct 13. PMID: 37866328.
14. Li Q#, Fang W#, Chen S, Li G, Jiang C, Zhuang Y, Li L, Liu P, Guo X, Hu G, Liu P,Gao X*. Characterization of Escherichia coli pathogenicity and drug resistance in yolk peritonitis. Poult Sci. 2024 Apr 27;103(7):103814. doi: 10.1016/j.psj.2024.103814.
15. Cao X#, Zheng S#, Zeng Y, Shi Y, Du J, Huang C, Shen Y, Liu P, Guo X,Gao X*. Effects of chronic Cr and Ni co-exposure on liver inflammation and autophagy in mice by regulating the TLR4/mTOR pathway. Sci Total Environ. 2024 May 20;926:171921. doi: 10.1016/j.scitotenv.2024.171921. （
16. Chen Y#, Feng C#, Huang C, Shi Y, Omar SM, Zhang B, Cai G, Liu P, Guo X*,Gao X*. Preparation of polyclonal antibodies to chicken P62 protein and its application in nephropathogenic infectious bronchitis virus-infected chickens. Int J Biol Macromol. 2024 May 18;271(Pt 2):132515. doi: 10.1016/j.ijbiomac.2024.132515.
17. 高晓娜#（第一作者）,郭小权.一磷酸腺苷激活的蛋白激酶对动物糖脂代谢的调节作用[J].动物营养学报,2017,29(12):4287-4294.
Presiding over or participating in scientific research projects and talent planning projects：
[1]国家自然科学基金青年项目：热应激干扰PPARγ-NLRP3信号轴致三黄鸡肠道黏膜屏障功能损伤的机制及染料木素的保护作用（32202880），2023.01-2025.12，30万，在研，主持；
[2]国家重点研发计划子任务：畜禽群发普通病防控技术研发与应用-2（2023YFD1801100），2023.12-2027.12，25万，在研，主持；
[3]江西省自然科学基金青年基金：柚皮素激活PPARα介导的线粒体动力学缓解热应激导致肠道屏障损伤的机制（20224BAB215056）, 2023.01-2025.12，10万元,在研，主持；
[4] 江西省教育厅科技计划项目重点项目：肉鸽的几种主要病原性疾病的同步快速分子诊断方法的建立与应用（GJJ2200407）, 2023.01-2025.12，5万元，在研，主持；
[5] 江西省教育厅教改课题：线上线下混合课堂模式下兽医产科学教学改革与实践（JXJG-22-3-15），2023.01-2024.12，2万元,在研，主持；
[6] 江西省教育厅,江西省教育厅科技计划项目，染料木素通过调控Muc2对禽大肠杆菌致肠炎的保护机制研究（GJJ210415）, 2022.01- 2024.12，3万元，在研，主持；
[7]江西农业大学人才引进启动项目，30万，在研，主持；
[8]国家自然科学基金地区项目：ACSL4和GPX4介导的脂质过氧化促进铁死亡在NIBV致痛风鸡肾脏损伤中的调控作用机制（32360906），2024.01-2027.12，32万，在研，参与；
[9]江西省现代农业产业技术体系项目，2021年省现代农业产业技术体-家禽产业技术体系质量安全与环境控制岗，JXARS，，90.0万元，在研，参与；
[10]江西省重点研发计划：肉鸭养殖提质增效关键技术研发与集成示范（20224BBF62003），2023.01-2025.12，100万，在研，参与。
