Wei lili Ph.D. (China)

hbliliwei@163.com

College of Animal Science & Technology, Jiangxi Agricultural University

1101 Zhimin Road, Nanchang, Jiangxi Province, CHINA 330045

Education

2004/9-2008/6 Doctoral programs of study, College of Fisheries, Huazhong Agricultural University,Majoring in Aquaculture.

2001/9-2004/6 Postgraduate programs of study, College of Fisheries, Huazhong Agricultural University,Majoring in Aquaculture.

1996/9-2000/6 Undergraduate student in Changjiang University (the former name is Hubei Agricultural College), majoring in aquaculture, Bachelor of Science,Majoring in Aquaculture.

WORKING EXPERIENCE

2014/12-present Associate professor in College of Animal Science & Technology, Jiangxi Agricultural University, China.

2015/9-2016/9 University of Tromsø UIT,visiting scholar

2008/11- 2014/12 Lecturer in College of Animal Science & Technology, Jiangxi Agricultural University, China.

PUBLICATIONS

1. Lin C, Fu J, Liu L, Wang H,Wei L*. Disruption of intestinal structure, tight junction complex, immune response and microbiota after chronic exposure to copper in swamp eel (Monopterus albus). Fish Shellfish Immunol. 2023, 143,109182.

2. Jianping Fu, Jun Chen, Xinyan Meng, Zhang Luo, Yi Liu*,Lili Wei*. Transcriptiomics analysis reveals immune regulation and cell death regulation of IFNg inPelodiscus sinensisSTA cells. Aquaculture 2023, 577: 739919.

3. Liu L, Fu J P, Tang QY, Wang H, Lin CG,Wei LL*.Combined transcriptomics and metabolomics analysis reveals lipid metabolic disruption in swamp eel (Monopterus albus) under chronic waterborne copper exposure. Aquatic Toxicology, 2023, 106520. doi: 10.1016/j.aquatox.2023.106520.

4. Jianping Fu, Jun Chen, XinYan Meng, Zhang Luo, Yi Liu*,Lili Wei*. Molecular identification and functional analysis of X-linked inhibitor of apoptosis -associated factor-1 (XAF1) in grass carp,Ctenopharyngodon idella. Fish and Shellfish Immunology, 2023, 134:108635.

5. Lili Wei, Jianping Fu, Li He, Hui Wang, Jiming Ruan, Fugui Li, Huadong Wu. Microcystin-LR-induced autophagy regulates oxidative stress, inflammation, and apoptosis in grass carp ovary cellsin vitro. Toxicology in Vitro. 2023, 87: 105520.

6. Yi Liu，Jing Guo, Wenjin Liu, Fengjie Yang, Yunyun Deng, Yunlong Meng, Bo Cheng, Jianping Fu, June Zhang, Xinjun Liao,Lili Wei*, huiqiang Lu*. Effects of haloxyfop-p-methyl on the developmental toxicity, neurotoxicity, and immunotoxicity in zebrafish. Fish and shellfish Immunology. 2023,132: 108466.

7. Yi Liu, Jing Guo, June Zhang, Yunyun Deng, Guanghua Xiong, Jianping Fu,Lili Wei*, Huiqiang Lu*. Chlorogenic acid alleviates thioacetamide-induced toxicity and promotes liver development in zebrafish (Danio rerio) through the Wnt signaling pathway. Aquat Toxicol. 2022, 242:106039.

8. Liu L, Zhou Q, Lin C, He L,Wei L*. Integrative analyses of gene expression and alternative splicing to gain insights into the effects of copper on hepatic lipid metabolism in swamp eel (Monopterus albus). Aquaculture, 2021, 546(Suppl. 1):737367.

9. Liu L, Zhou Q, Lin C, He L,Wei L*. Histological alterations, oxidative stress, and inflammatory response in the liver of swamp eel (Monopterus albus) acutely exposed to copper. Fish Physiology and Biochemistry. 2021, 47(6):1865-1878.

10. Li He, Lin Liu, Changgao Lin, Jiming Ruan, Ximei Liang, Yin Zhou,Lili Wei*. Effects of MC-LR on histological structure and cell apoptosis in the kidney of grass carp (Ctenopharyngodon idella). Fish Physiology and Biochemistry. 2020,46(6): 2005-2014.

11. Wei L, He L, Fu J, Ruan J, Liu L, Zhong Q*. Molecular characterization of caspase-8-like and its expression induced by microcystin-LR in grass carp (Ctenopharygodon idella). Fish Shellfish Immunol. 2019, 89:727-735.

12. Jianping Fu, Wenjin Liu, Hao Cui, Chunhui Song, Yi Liu*,Lili Wei*. Characterization and functional analysis of liver-expressed antimicrobial peptide-2 (LEAP-2) inPelodiscus sinensis. Aquaculture 2019, 511: 734263.

13. Xuan Chen, Shaoming Fang,Lili Wei*, Qiwang Zhong*. Systematic evaluation of the gut microbiome of swamp eel (Monopterus albus) by 16S rRNA gene sequencing. Peer J. 2019, DOI 10.7717/peerj.8176.

14. LiLi Wei, Yi Liu, Shengwei Zhong, Huadong Wu, Jiming Ruan, Mingyue Liu, Qiubai Zhou*, Qiwang Zhong*. Transcriptome analysis of grass carp provides insights into the immune-related genes and pathways in response to MC-LR induction.Aquaculture 2018, 488: 207-216.

15. Xuan Chen, Chongde Lai, Yulan Wang, Lili Wei*, Qiwang Zhong*. Disinfection effect of povidone-iodine in aquaculture water of swamp eel (Monopterus albus). Peer J. 2018, DOI 10.7717/peerj.552 .

16. Lili Wei, Yi Liu, Zirui Wang, Jiming Ruan, Huadong Wu, Qiwang Zhong*. Histopathological changes and transcriptional alterations of three coagulation factors in zebrafish (Danio rerio) following short-term exposure to MC-LR. Acta Ecologica Sinica. 2017, 37: 120-124.

17. Wei LiLi, Liu Yi, Wu HuaDong, Zhou QiuBai*. Molecular characterization and expression of a long type peptidoglycan recognition protein (PfPGRP-L) from yellow catfish,Pelteobagrus fulvidraco. Acta Hydrobiologica Sinica. 2016, 40(1):42-49.

18. LiLi Wei, Dave Hoole and Baojian Sun*. Identification of apoptosis-related genes and transcription variations in response to microcystin-LR in zebrafish liver. Toxicol and Ind Health. 2014, 30(9): 777-784.

19. Ximei Liang, Jun Zhang, Feng Guo,Lili Wei, Qiubai Zhou. Oxidative stress and inflammatory responses in the liver of swamp eel (Monopterus albus) exposed to carbon tetrachloride. Aquaculture 496 (2018) 232-238.

RESEARCH ACTIVITIES (PROJECT INCHARGE)

1. The study on the effects of copper on the lipid metabolism of liver in swamp eel and its mechanisms of action based on PPARα /γ signaling pathway.2020.01-2023.12. Financed by the National Natural Science Foundation of China (No.31960729). Project manager.

2. The role and regulation mechanisms of autophagy in fish’s hepatocytes induced by MC-LR.2018.01-2021.12. Financed by the National Natural Science Foundation of China (No.31760764). Project manager.

3. Study of mechanisms and regulation of GRP78 on apoptosis mediated by endoplasmic reticulum stress in liver of grass carp induced by microcystins. 2015.1-2018.12. Financed by the National Natural Science Foundation of China (No.31460146). Project manager.

4. Splicing isoforms of PGRP-L and their antibacterial actions in yellow catfish. 2015.1-2017.12. Financed by Jiangxi Province Educational Committee. (No. GJJ14286). Project manager.

5. Study on the Screening and characterization of immune-related genes in grass carp caused gill-rot disease. 2011.1-2013.12. Financed by Jiangxi Province Educational Committee (No. GJJ11087). Project manager.

6. Study on the cloning and expression analysis of a long type peptidoglycan recognition protein (PGRP-L) and its immune regulation in split head disease of yellow catfish. 2012.1-2014.12. Financed by Natural Science Foundation of Jiangxi Province (No. 20114BAB214002). Project manager.

7. Study on the early diagnosis, warning and immune prevention and control technology in the split head disease of yellow catfish- a follow up. 2012.1-2014.12. Financed by Science and Technology Support Program of Jiangxi (No. 20121BBF60034). Project manager.

8. Study on the early diagnosis, warning and immune prevention and control technology in the split head disease of yellow catfish. 2011.1-2014.12. Financed by Science and Technology Support Program of Jiangxi (NO.20111BBF60021). Project manager.

RESEARCH DIRECTION

Healthy aquaculture of aquatic animals, focusing on the prevention and control of freshwater fish diseases,the monitoring and evaluation of fishery ecological environment.