LINGBAO Kong PH.D

Professor, Millions of Talent Project Jiangxi Province candidate

1991-1995   Xingyang Normal University, BSc of Biology

2002-2007  Wuhan University, PhD of Microbiology

2007-2008   Postdoctoral scholar, The University of Chicago, USA

2013-2014   Visiting scholar, National  institute of  infectious disease , Japan

2022-2023  Visiting scholar, National University of Singapore, Singapore

2008-present  Professor,College of Bioscience and Engineering, Jiangxi Agricultural University

Research interest

We have been doing the research on viruses, including Hepatitis C Virus. Japanese Encephalitis Virus, Porcine Epidemic Diarrhea virus and African Swine Fever Virus. The specific focus is virus-host interaction, antiviral drug and vaccine.

Selected publications

[1] Wang Y, Li Y, Li M, Wang K, Xiong J, Wang T, Wang Y, Guo Y, Kong L*, Li M*. A Combined Transcriptomic and Proteomic Analysis of Monkeypox Virus A23 Protein on HEK293T Cells. Int J Mol Sci. 2024 Aug 8;25(16):8678.(IF=4.9）

[2] Wang Y, Zhang J, Li M, Jia M, Yang L, Wang T, Wang Y, Kang L, Li M*, Kong L*.Transcriptome and proteomic analysis of mpox virus F3L-expressing cells. Front Cell Infect Microbiol. 2024 Feb 13:14:1354410..(IF=4.6）

[3] Jiang H, Wang T, Kong L*, Li B*, Peng Qi*. Reverse Genetics Systems for Emerging and Re-Emerging Swine Coronaviruses and Applications.Viruses. 2023 Sep 26;15(10):2003. (IF=3.8）

[4] Li Y, Gladue DP, Li S, Deng L, Shen C, Aguilar PV, Wang T, Kong L*. Editorial: Insights of important mammalian viruses: Infection, pathogenesis and drugs. Front Microbiol. 2023 Feb 21;14:1147109. ((IF=4.0）

[5] Feng T, Li M, Zhang L, Li S, Yang Z, Kang L, Guo Y, Kong L*, Wang T*. Immunity of two novel hepatitis C virus polyepitope vaccines. Vaccine. 2022 Oct 12;40(43):6277-6287. (IF=5.5）

[6] Li M, Weng S, Wang Q, Yang Z, Wang X, Yin Y, Zhou Q, Zhang L, Tao F, Li Y, Jia M, Yang L, Xin X, Li H, Kang L, Wang Y*, Wang T*, Li S*, Kong L*. Reduced binding activity of vaccine serum to Omicron Receptor-Binding Domain.  Front Immunol  2022 Jul 28;13:960195. (IF=7.3）

[7] Yang Z, Ouyang T, Aoyagi H, Wang T, Xing X, Zhang Y, Wang Y, Li Y, Aizaki H, Li S*, Kong L*. Cellular OCIAD2 protein is a proviral factor for hepatitis C virus replication. Int J Biol Macromol. 2021 Oct 1;188:147-159. (IF=8.02）

[8] Wan J, Wang T, Xu J, Ouyang T, Wang Q, Zhang Y, Weng S, Li Y, Wang Y, Xin X, Wang X, Li S*, Kong L*. Novel Japanese encephalitis virus NS1-based vaccine: Truncated NS1 fused with E. coli heat labile enterotoxin B subunit. EBioMedicine. 2021 May; 67:103353. doi: 10.1016/j.ebiom.2021.103353. (IF=11.2）

[9] Kong L, Aoyagi H, Yang Z, Ouyang T, Matsuda M, Fujimoto A, Watashi K, Suzuki R, Arita M, Yamagoe S, Dohmae N, Suzuki T, Suzuki T, Muramatsu M, Wakita T, Aizaki H*. Surfeit 4 contributes to the replication of hepatitis C virus using double membrane vesicles. J Virol. 2020 Jan 6;94(2). pii: e00858-19. doi: 10.1128/JVI.00858-19. (IF=5.1）

[10] Kong L, Fujimoto A, Nakamura M, Aoyagi H, Matsuda M, Watashi K, Suzuki R, Arita M, Yamagoe S, Dohmae N, Suzuki T, Sakamaki Y, Ichinose S, Suzuki T, Wakita T, Aizaki H*. Prolactin regulatory element binding protein is involved in hepatitis C virus replication compartment by interacting with NS4B. J Virol. 2016 Jan 6;90(6):3093-111. (IF=4.6）

[11] Wang Q, Xin X, Wang T, Wan J, Ou Y, Yang Z, Yu Q, Zhu L, Guo Y, Wu Y, Ding Z, Zhang Y, Pan Z, Tang Y*, Li S*, Kong L*. Japanese Encephalitis Virus Induces Apoptosis and Encephalitis by Activating the PERK Pathway. J Virol. 2019 Aug 13;93(17). （IF=4.5）

[12] Guo F, Yu X, Xu A, Xu J, Wang Q, Guo Y, Wu X, Tang Y, Ding Z, Zhang Y, Gong T, Pan Z, Li S*, Kong L*. Japanese encephalitis virus induces apoptosis by inhibiting Foxo signaling pathway. Vet Microbiol. 2018 Jul;220:73-82.（IF=2.79）

[13] Li S*, Kong L*, Yu X. The expanding roles of endoplasmic reticulum stress in virus replication and pathogenesis. Crit Rev Microbiol. 2015 Jun;41(2):150-64. (IF=8.19）

[14] Li S, Kong L*, Yu X, Zheng Y*. Host-virus interactions: from the perspectives of epigenetics. Rev Med Virol. 2014 Jul;24(4):223-41.（IF= 5.57）

[15] Kong L*, Li S*, Liao Q, Zhang Y, Sun R, Zhu X, Zhang Q, Wang J, Wu X, Fang X, Zhu Y.  Oleanolic acid and ursolic acid: novel Hepatitis C virus antivirals that inhibit NS5B activity. Antiviral Res. 2013 Apr;98(1):44-53. （IF=3.43）

[16] Li S, Yu X, Guo Y, Kong L*. Interaction Networks of Hepatitis C Virus NS4B: Implications for Antiviral Therapy. Cell Microbiol  2012 ;14(7):994-1002.（IF= 4.81)  

Selected honors and awards

[1]  China Association of Returned Scholars (CARS) "Innovation and Entrepreneurship" Competition Prize，2021‌

[2] Research Awards in Jiangxi Province, 2015, 2010, 2008

Contact information

Tel: + 86 791 83828079

E-mail: lingbaok@hotmail.com, lingbaok@mail.jxau.edu.cn