Bin Zhang PH.D.
Associate professor
Research Focus:
· Construction of industrial microbial chassis cells, such as Corynebacterium glutamicum and Pseudomonas putida.
· Green biomanufacturing of natural products and synthetic biology.
Education:
· 2015/9–2019/6: PhD in Biochemistry and Molecular Biology, East China University of Science and Technology
· 2012/9–2015/6: Master's in Biochemical Engineering, Jiangxi Normal University
· 2008/9–2012/6: Bachelor's in Biotechnology, East China University of Technology
Courses Taught:
· Graduate Students: Metabolic Engineering, Microbial Engineering
· Undergraduate Students: Introduction to Bioengineering, Modern Industrial Fermentation Control, Genetic Engineering
Selected publications
(1) Xu Shunqing#, Zhang Bin#, Chen Wanhe, Ye Kai, Shen Jian, Liu Pengfu, Wu Jiequn, Wang Hong, Chu Xiaohe*. Highly efficient production of ectoine via an optimized combination of precursor metabolic modules in Escherichia coli BL21. Bioresour Technol. 2023 Dec; 390:129803.
(2) Qi Sheng, Linxin Yi, Bin Zhong, Xiaoyu Wu, Liming Liu*, Bin Zhang*. Shikimic acid biosynthesis in microorganisms: Current status and future direction. Biotechnol Adv. 2022 Dec 1:108073.
(3) Libin Nie, Yutong He, Lirong Hu, Xiangdong Zhu, Xiaoyu Wu, Bin Zhang*. Improvement in L-ornithine production from mannitol via transcriptome-guided genetic engineering in Corynebacterium glutamicum. Biotechnol Biofuels Bioprod. 2022 Sep 19;15(1):97.
(4) Libin Nie, Kexin Xu, Bin Zhong, Xiaoyu Wu, Zhongtao Ding, Xuelan Chen, Bin Zhang*. Enhanced l-ornithine production from glucose and sucrose via manipulation of the fructose metabolic pathway in Corynebacterium glutamicum. Bioresour Bioprocess, 2022; 9(1), 1-12.
(5) Yan Jiang, Qi Sheng, Xiao-Yu Wu, Bang-Ce Ye, Bin Zhang*. L-arginine production in Corynebacterium glutamicum: manipulation and optimization of the metabolic process. Crit Rev Biotechnol. 2021; 41:172-185.
(6) Qi Sheng, Xiao-Yu Wu, Yan Jiang, Zhimin Li, Fei Wang, Bin Zhang*. Highly efficient biosynthesis of l-ornithine from mannitol by using recombinant Corynebacterium glutamicum. Bioresour Technol. 2021; 327:124799.
(7) Qi Sheng, Xiao-Yu Wu, Xinyi Xu, Xiaomin Tan, Zhimin Li, Bin Zhang* Production of l-glutamate family amino acids in Corynebacterium glutamicum: Physiological mechanism, genetic modulation, and prospects. Synth Syst Biotechnol, 2021; 6(4), 302-325.
(8) Yan Jiang#, Ming-Zhu Huang#, Xue-Lan Chen, Bin Zhang*. Proteome analysis guided genetic engineering of Corynebacterium glutamicum S9114 for tween 40-triggered improvement in ʟ-ornithine production. Microb Cell Fact. 2020, 19:2.
(9) Bin Zhang, Ge Gao, Bang-Ce Ye*. Metabolic engineering of Corynebacterium glutamicum S9114 to enhance the production of ʟ-ornithine driven by glucose and xylose. Bioresour Technol. 2019; 284:204-213.
(10) Bin Zhang, Li-Quan Ren, Miao Yu, Ying Zhou, Bang-Ce Ye*. Enhanced ʟ-ornithine production by systematic manipulation of ʟ-ornithine metabolism in engineered Corynebacterium glutamicum S9114. Bioresour Technol. 2018; 250:60-68.
Contact information
Email: zhangbin2919@163.com
