Ganjun Yuan
Professor
Department of Pharmaceutical Engineering
Biotechnological Engineering Center for Pharmaceutical Research and Development
gyuan@jxau.edu.cn
Ganjun Yuan had obtained a doctoral degree from Hainan University, and now works as a chief professor of Jiangxi Agricultural University. From 2015 to 2016, he studied in Louisiana State University Health Science Center (New Orleans) as a visiting scholar in microbial pharmacology. His main research fields are follows: (1) Natural medicines and microbial medicines; (2) Drug research for preventing bacterial resistance; (3) Research and Practice on Chinese Medicine. In these fields, he has been hosted 6 projects funded by the National Natural Science Foundation of China, and has 9 invention patents and one prescription curing diabetes. Another, he won one outstanding abstract award from the Asia Pacific Foundation for Infectious Diseases and the Korean Society of infectious Diseases on the conference of ISAAR & ICIC 2017. Recently, he established a theoretical system on drug combination to prevent antimicrobial resistance. As a keynote speaker, he put forward a concept of “One earth, one Health” for the first time on the conference of IC2AR 2024.
Some important papers:
Yi H, Yuan G, Li S, Xu X, Guan Y, Zhang L, Yan Y. Drug combinations to prevent antimicrobial resistance: various correlations and laws, and their verifications, thus proposing some principles and a preliminary scheme. Antibiotics. 2022; 11(10): 1279.
Yuan, G., Guan, Y., Yi, H. Lai S., Sun Y., Cao S. Antibacterial activity and mechanism of plant flavonoids to gram-positive bacteria predicted from their lipophilicities. Sci Rep 2021; 11, 10471.
Yan Y, Xia X, Fatima A, Zhang L, Yuan G, Lian F, Wang Y. antibacterial activity and mechanisms of plant flavonoids against gram-negative bacteria based on the antibacterial statistical model. Pharmaceuticals 2024; 17(3): 292.
Luo Z, Li P, Zhang D, Zhu J, Wang W, Zhao W, Li P, Yuan G. A novel antimicrobial mechanism of azalomycin F acting on lipoteichoic acid synthase and cell envelope. Molecules 2024; 29(4): 856.
Sun Y, Xia X, Yuan G, Zhang T, Deng B, Feng X, Wang Q. Stachydrine, a bioactive equilibrist for synephrine, identified from four citrus chinese herbs. Molecules 2023; 28(9): 3813.
Yuan G., Xu L., Xu X., Li P., Zhong Q., Xia H., Hu Y., Li P., Song X., Li J., Liu Q. Azalomycin F5a, a polyhydroxy macrolide binding to the polar head of phospholipid and targeting to lipoteichoic acid to kill methicillin-resistant Staphylococcus aureus. Biomed Pharmacother 2019; 109: 1940-1950.
Xu, X., Xu, L., Yuan, G. Yimin Wang, Qu Y., Zhou M. Synergistic combination of two antimicrobial agents closing each other’s mutant selection windows to prevent antimicrobial resistance. Sci Rep 2018, 8, 7237.
